Tutorial Name: Irreversible Cell Injury
ConceptName: Fibrinoid necrosis
Slide Name: Malignant hypertension (high)

Image Description: Fibrinoid necrosis of arterioles (brightly eosinophilic material in the vessel wall). Fibrin has extravasated from the lumen into the damaged and necrotic vessel wall. This process follows endothelial and vessel wall injury due to the very high systemic blood pressure.

 
Structures Structure Descriptions
arteriole The arteriole is approaching the glomerulus from the lower right. Note eosinophilic fibrinoid necrosis in the dilated wall of the vessel. Fibrin and necrotic debris fill the lumen.
glomerulus This is a bloodless glomerulus; the capillary loops are filled with eosinophilic material and are collapsed.

Related Pathology Images: Histology Images to Compare:
Malignant Hypertension (high)
Malignant Hypertension (high3)
Normal kidney

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