Tutorial Name: Macropatterns of Injury
ConceptName: Specificity of injury pattern
Slide Name: Biliary Atresia (low)

Image Description: The portal areas are widened into fibrous septae containing proliferating bile ducts. This develops as a compensatory response to extrahepatic bile duct atresia.

 
Structures Structure Descriptions
expanded portal areas Expanded portal areas with fibrosis are seen at upper left-to-center. While the extrahepatic bile duct is atretic, reactive bile duct proliferation occurs inside the portal areas, accompanied by reactive fibrosis.
hepatocytes The hepatocytes retain their lobular structure, with plates surrounded by sinusoids.

Related Pathology Images: Histology Images to Compare:
Acetaminophen tox. Liver (low)
Acetaminophen tox. Liver (high)
Central Necrosis (low)
Central Necrosis (high)
Biliary Atresia (low)
Normal Liver: Liver Parenchyma (H&E)

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