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Reversible Cell Injury:
Introduction

• Cell edema
• Loss of normal cell features
• Abnormal accumulations of metabolites
• Evaluation

Irreversible Cell Injury:
Introduction

• Coagulative necrosis
• Apoptosis
• Liquefactive necrosis
• Caseous necrosis
• Fibrinoid necrosis
• Evaluation

Macropatterns of Injury:
Introduction

• Ulceration
• Infarction
• Abscess formation
• Specificity of injury pattern
• Evaluation

Reactive/Regenerative Changes:
Introduction

• Mitotic figures
• Cell flattening and simplification
• Cell enlargement
• Evaluation

Cellular adaptations:
Introduction

• Atrophy
• Hypertrophy
• Hyperplasia
• Metaplasia
• Evaluation

Pigments/cellular or tissue accumulations:
Introduction

• Carbon
• Iron
• Bile
• Minerals and Salts
• Protein
• Evaluation

Inflammation:
Introduction

• Types of Inflammatory Cells
• Patterns of Inflammation
• Evaluation

Chronic inflammation/Repair:
Introduction

• Chronic Inflammation
• Mulinucleated giant cells
• Other types of giant cells
• Granulomatous inflammation
• Tissue Repair, reconstitution, and regeneration
• Evaluation

Neoplasia:
Introduction

• Hyperplasia
• Metaplasia
• Dysplasia
• Benign tumors
• In situ carcinoma
• Invasive carcinoma
• Metastasis
• Differentiation of tumors
• Evaluation

Final Evaluation

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