1. Enhancing Humane Science: Improving Animal Research - Opening 2. Introduction to Humane Science 3. Rodent Surgery – Quality Matters 4. Post-Procedural Care 5. Pain and Distress: Measurement, Avoidance and Relief 6. Impact of Stress on Quality of Data 7. Humane Endpoints in Animal Research 8. Animal Welfare – The Five Freedoms 9. Environmental Enrichment in Rodent Studies: Functional Outcomes 10. Overview of Non-Invasive Imaging in Rodents 11. In Vitro and Other Replacement Approaches 12. Experimental Design, Basic Statistics, & Sample Size Determination

Alan M. Goldberg/James Owiny Andrew Rowan/Alan M. Goldberg Randy Brown Sylvia Singletary/Christian Newcomer Norman Peterson Andrew Rowan James Owiny Julie Watson Tomás Guilarte Kathy Gabrielson Alan M. Goldberg/James Yager Karl W. Broman